发明名称 Conjugates of metallo:thionein and biologically active molecules
摘要 Conjugate (I) of a target-seeking biologically active molecule (II) and metallothionein (III), or a fragment of (III), is new. The metal, or part of it, in the (III) or its fragment is a trace label metal having sufficient affinity for (III) or its fragment to bind to it. Conjugate (IV) of a target-seeking biologically active molecule (V) and (III), or its fragment, is new when all the metal in the (III), or its fragment, is non-radioactive and has an affinity for (III) less than the Tc, Ag, Au, Hg or cupric cations.
申请公布号 ES8605105(A1) 申请公布日期 1986.08.01
申请号 ES19470005365 申请日期 1984.10.05
申请人 E.I. DU PONT DE NEMOURS AND COMPANY 发明人
分类号 G01N33/532;A61K38/00;A61K38/22;A61K39/395;A61K39/44;A61K47/48;A61K51/00;A61K51/10;C07K1/113;C07K14/00;C07K14/575;C07K16/00;C07K19/00;G01N33/553;(IPC1-7):G01N33/60;G21H5/02 主分类号 G01N33/532
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