New pseudo-polysaccharide cpds. with glucosidase inhibiting activity

摘要

Pseudooligosaccharides of formula (I) and their physiologically acceptable acid salts are new, where l = 1 or 2; m = 1-3; n = 1-20. Also new is the microorganism Streptomyces galbus subspecies FH 1716 (DSM 3007). - (I) are made by fermenting appropriate Streptomycetes, esp. DSM 3007, esp. under submerged, aerobic conditions. Fermentation is pref. at 20-35 deg.C and pH 6-9, typically for 1-10 days. (I) are present in both the mycelium and, mostly in the culture filtrate. They can be recovered by usual methods, esp. first adsorption onto a polystyrene resin, then elution with buffers or aq. organic solvents. Individual (I) can be sepd. by e.g. ion-exchange or molecular-sieve chromatography.