| 摘要 |
<p>Compounds of the formula < IMG > I wherein one of the double bonds indicated by broken lines is present in 4,5 or 5,6-position, R is hydrogen or lower alkyl, R1 is methyl, hydrogen or hydroxy; R2 is hydrogen, methyl or fluoro; and R21 is hydrogen, fluoro, trifluoromethyl or methyl; with the proviso that when R21 is trifluoromethyl, R2 is hydrogen or methyl, their pharmaceutically acceptable salts, optical antipodes or racemates are useful as anti-secretory agents, anti-hype-tensives, anti-ulcerogenic agents and blood platelet aggregation inhibiting agents. They can be prepared from compounds of the formula < IMG > II</p> |
