发明名称 |
PROCESS FOR THE PREPARATION OF HYDROCHLORIDES |
摘要 |
<p>PROCESS FOR THE PREPARATION OF HYDROCHLIRIDES A b s t r a c t The invention relates to a process for the preparation of hydrochlorides, i.e. of acid addition salts formed with hydrochloric acid, particularly of compounds containing a protonatable nitrogen atom According to the process of the invention a compound useful to form a hydrochloride and being suitably in the form of a derivative containing protonatable nitrogen atom or in the form of a salt is reacted with a sulphonyl compound of the formula Q - SO2 - Cl, wherein Q stands for a hydroxyl, C1-4 alkyl or an aryl group, the latter being optionally substituted by a C1-4 alkyl group, in a solvent, in the presence of an alcohol, whereupon the hydrochloride obtained is recovered in a known manner.</p> |
申请公布号 |
CA1208626(A) |
申请公布日期 |
1986.07.29 |
申请号 |
CA19840452850 |
申请日期 |
1984.04.26 |
申请人 |
SZARVAS, MIKLOS;HORVATH, EVA (NEE FEHER);CSEKE, LASZLO;BALINT, JANOS;FABIAN, FERENC;KUN, LAJOS |
发明人 |
SZARVAS, MIKLOS;HORVATH, EVA (NEE FEHER);CSEKE, LASZLO;BALINT, JANOS;FABIAN, FERENC;KUN, LAJOS |
分类号 |
C07D295/02;C07B31/00;C07B43/00;C07B61/00;C07C67/00;C07C229/06;C07C237/26;C07C243/10;C07C303/08;C07D207/22;C07D211/70;C07D211/88;C07D223/26;C07D223/28;C07D489/02;C07D489/04;C07D495/04;C07D499/00;C07D513/04;C07H15/16;C07H15/224;C07H15/234;C07H15/238;C07H15/252;C07H17/08;C07J41/00;C07J75/00;(IPC1-7):C07K7/64;C07H15/20;C07D501/04 |
主分类号 |
C07D295/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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