发明名称 |
5-AMINOMETHYL-2,3-DIHYDRO-2-OXO-1H-IMIDAZOLE-4-CARBOXYLIC ACID DERIVATIVES |
摘要 |
2,3-Dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives having a (substituted amino)methyl substituent at the 5-position, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appropriate amine with a 5-(bromomethyl)-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid ester or amide. |
申请公布号 |
DE3271755(D1) |
申请公布日期 |
1986.07.24 |
申请号 |
DE19823271755 |
申请日期 |
1982.05.03 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
GRISAR, MARTIN J.;DAGE, RICHARD C.;SCHNETTLER, RICHARD A. |
分类号 |
A61K31/415;A61K31/44;A61K31/4427;A61K31/445;A61K31/495;A61K31/535;A61P7/02;A61P9/12;C07D233/70;C07D233/90;C07D401/06;(IPC1-7):C07D233/90 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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