发明名称 |
4-(4-PHENYL-1-PIPERIDINYL)METHYL-5-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES |
摘要 |
<p>1,3-Dihydro-2H-imidazol-2-ones having 5-acyl and 4-(4-phenyl-1-piperidinyl)methyl substituents, are useful as cardiotonics, antihypertensives and antithrombotic agents. The compounds are obtained by the reaction of an appropriate substituted piperidine with a substituted 4-bromomethyl-1,3-dihydro-2H-imidazol-2-one.</p> |
申请公布号 |
EP0064707(B1) |
申请公布日期 |
1986.07.23 |
申请号 |
EP19820103743 |
申请日期 |
1982.05.03 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
GRISAR, J. MARTIN;DAGE, RICHARD C.;SCHNETTLER, RICHARD A. |
分类号 |
C07D409/14;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61P7/02;A61P9/00;A61P9/04;A61P9/12;C07D233/70;C07D401/06;C07D401/14;C07D405/14;(IPC1-7):C07D401/06;A61K31/415;A61K31/44;C07D405/06;C07D409/06 |
主分类号 |
C07D409/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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