发明名称 COMPOUNDS AND METHOD
摘要 A compound of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof, wherein R<A> is a group of formula (a): <CHEM> wherein T represents a group of formula (b): Q-X<1>-@@-CH2 (b) wherein Q is <CHEM> and where R<1> is a hydrogen or halogen atom or a -CF3, OR<4>, NHR<4>, -NHCOR<4>, -NHCONH2, NHSO2 R<4>, CH2OR<4> or -CH2SO2 R<4> group: R<2> is a hydrogen or halogen atom or an -OR<4> group; R<3> is a hydrogen or halogen atome; and R<4> is hydrogen, C1-6 alkyl or benzyl; X<1> is a bond or -OCH2-; X<2> is a group of formula -CR<5>R<6>-CH2-A- wherein R<5> and R<6> are independently hydrogen or methyl; and A is a bond, -CH2-, or O; T<1> represents a hydrogen atom or a group of formula (b) as defined above in respect of T, such that T<1> and T may be the same or different; R<C> represents a group (a) as defined above in respect of R<A>, such that R<C> and R<A> may be the same or different; provided that when R<A> and R<C> each represent a group of formula: <CHEM> wherein R<2> is oH or -O-benzyl; then when A is a bond, -CH2- or -O, R<1> is not -CH2OH or NHSO2-C1-4 alkyl; processes for the preparation of such compounds and their use in medicine and agriculture.
申请公布号 GR860797(B) 申请公布日期 1986.07.21
申请号 GR19860100797 申请日期 1986.03.26
申请人 BEECHAM GROUP P.L.C 发明人 SMITH GLYNN DAVID;WHITE MARY SUSAN
分类号 A23K1/16;A61K31/135;A61K31/165;A61K31/17;A61K31/18;A61P3/00;A61P3/04;A61P3/08;A61P15/00;C07C67/00;C07C213/00;C07C215/30;C07C215/68;C07C217/32;C07C217/70;C07C231/00;C07C231/02;C07C231/12;C07C233/25;C07C233/34;C07C233/43;C07C301/00;C07C303/40;C07C311/08;C07C311/13;C07C313/00;C07C315/04;C07C317/22;C07C317/32 主分类号 A23K1/16
代理机构 代理人
主权项
地址