| 摘要 |
<p>The compounds have the general formula I <IMAGE> in which R<1> is a hydrogen or halogen atom, an alkyl or alkoxy group with, in each case, 1 to 4 carbon atoms, an amino group or acylamino group, R<2> and R<3>, which can be identical or different, are a hydrogen atom or an alkyl group with 1 to 3 carbon atoms, R<4> is a phenyl group or a substituted phenyl group which can be substituted by one halogen atom, one or two alkoxy groups, one methylenedioxy group, one hydroxyl group, or is a pyridyl group, an indolyl group, a 1,2-benzisoxazolyl group which is optionally substituted by one halogen atom, the benzimidazol-2-one, 1,4-benzodioxane or benzoxolane residue, X is an oxygen atom or a single bond and n is the numbers 0, 1, 2 or 3, and they and their acid addition salts block both alpha and beta receptors of the adrenergic system and are therefore suitable for treating hypertension, disturbances of blood flow, angina pectoris and coronary insufficiency.</p> |
