| 摘要 |
PURPOSE:To obtain advantageously the aimed compound in high selectivity and yield, by using a lower alcohol as a solvent in producing the titled compound useful as an intermediate for herficides through reaction of p- methylacetophenone with a halogenating agent in the solvent. CONSTITUTION:p-Methylacetophenone is reacted with a halogenating agent, preferably bromine or chlorine gas, in a lower alcohol such as methanol, ethanol, propanol and butanol (methanol and/or ethanol are preferred) at 0-50 deg.C, preferably 54n30 deg.C to obtain a p-methylphenacyl halide in extremely high selectivity and yield with supressing disproportionation reaction without using any troublesome operation such as recrystallization. The amount of the solvent to be used is 5-15mol, preferably 6.5-10mol and the amount of the halogenating agent to be used is 0.9-1.1mol, preferably equimolar, both based on 1mol p- methylacetophenone.
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