发明名称 Renin-inhibitory dipeptides, their preparation and use.
摘要 <p>Compounds of formula (I): &lt;CHEM&gt; (wherein m is 0 or 1 and R&lt;1&gt;-R&lt;5&gt; are a variety of organic groups) have the ability to inhibit the activity of renin and may thus be used to treat hypertension induced by failures in the renin-angiotensin system. They are prepared by conventional peptide synthesis routes.</p>
申请公布号 EP0186977(A2) 申请公布日期 1986.07.09
申请号 EP19850308759 申请日期 1985.12.02
申请人 SANKYO COMPANY LIMITED 发明人 MORISAWA, YASUHIRO;YABE, YUICHIRO;KATAOKA, MITSURU;IIJIMA, YASUTERU;KOKUBU, TATSUO;HIWADA, KUNIO
分类号 C07K5/062;A61K38/05;C07D233/54;C07D277/30;C07D295/185;C07K5/02;C07K5/065;(IPC1-7):C07C103/76;C07C149/23;C07D233/64;C07D295/12;C07D211/58;A61K31/395;A61K31/165 主分类号 C07K5/062
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