发明名称 |
Renin-inhibitory dipeptides, their preparation and use. |
摘要 |
<p>Compounds of formula (I): <CHEM> (wherein m is 0 or 1 and R<1>-R<5> are a variety of organic groups) have the ability to inhibit the activity of renin and may thus be used to treat hypertension induced by failures in the renin-angiotensin system. They are prepared by conventional peptide synthesis routes.</p> |
申请公布号 |
EP0186977(A2) |
申请公布日期 |
1986.07.09 |
申请号 |
EP19850308759 |
申请日期 |
1985.12.02 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
MORISAWA, YASUHIRO;YABE, YUICHIRO;KATAOKA, MITSURU;IIJIMA, YASUTERU;KOKUBU, TATSUO;HIWADA, KUNIO |
分类号 |
C07K5/062;A61K38/05;C07D233/54;C07D277/30;C07D295/185;C07K5/02;C07K5/065;(IPC1-7):C07C103/76;C07C149/23;C07D233/64;C07D295/12;C07D211/58;A61K31/395;A61K31/165 |
主分类号 |
C07K5/062 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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