Antiphlogistic/antipyretic/analgesic agents containing theobromine or theophylline derivatives as active ingredient

摘要

Treatment methods are disclosed which utilize antiphlogistic/antipyretic/analgesic agents containing as active ingredient theobromine and theophylline derivatives represented by the general formula: wherein one of A and B is -CH3 and the other of A and B is wherein R is a hydrogen atom or a lower alkyl group, Z is selected from the group consisting of (1) a group of the formula wherein X1 and X2 are the same or different and each represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom; (2) a pyridyl group; or (3) a group of the formula: wherein Y1 and Y2 may be the same or different and Y1 and Y2 are selected from the group consisting of a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group and a halogen atom, X is a nitrogen atom or a carbon atom, m is 2 or 3, and n is an integer of from 2 to 10, with the provisos that when (i) A is -CH3, m is 2, and (ii) when A is Z is not pyridyl and X is nitrogen, and acid addition salts thereof.