发明名称 |
PROCESS FOR SEPARATION OF PRECURSORS OF (ALPHA) AND (ALPHA)-2-(6-METOXI-2-NAPHTYLE)-PROPIONIC ACID |
摘要 |
(d)-2-(6-Methoxy-2-naphthyl)propionic acid and pharmaceutically acceptable salts thereof are prepared by resolving mixtures of (d)- and (1)-enantiomers of 2-(6-methoxy-2-naphthyl)propionic precursor acids or salts thereof with N-alkyl- or N-cycloalkyl-D-glucamines or salts thereof to isolate the corresponding (d)-2-(6-methoxy-2-naphthyl)propionic precursor acid which can be readily converted into (d)-2-(6-methoxy-2-naphthyl)propionic acid or a pharmaceutically acceptable salt thereof. |
申请公布号 |
YU117283(A) |
申请公布日期 |
1986.06.30 |
申请号 |
YU19830001172 |
申请日期 |
1983.05.26 |
申请人 |
SYNTEX PHARMACEUTICALS INTERNATIONAL |
发明人 |
VON MORZE H. |
分类号 |
C07B57/00;C07C51/487;C07C59/00;C07C59/52;C07C59/56;C07C59/64;C07C59/88;(IPC1-7):C07C63/595;A61K31/19 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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