摘要 |
<p>An apparatus for intraoperative diagnosis is described which comprises a refrigerating device adapted to sprinkle a cryogenic liquid on the surface of a slide whereby the surface of the slide is cooled to at least -4 DEG C. up to -8 DEG C., at least one cooling fan which increases the evaporation of the cryogenic liquid and permits to achieve the necessary hypothermia on the slide; an automatic appositor which permits to exert a measurable and graduated pressure onto the section of the organ which has been interposed between the appositor and the slide at the time in which the section has reached a predetermined temperature. The appositor is provided with means for varying automatically the pressure during the advance of the slide. The refrigerating device comprises a cylinder containing a cryogenic liquid. The invention also resides in the method of carrying out histological analysis which consists of placing a section of tissue under examination on a slide, cooling vigorously the slide whereby the tissue undergoes a thermic shock and exfoliates on the slide. Pressure is applied after the section of tissue has been cooled.</p> |