METHOD FOR STABILIZING TISSUE PLASMINOGEN ACTIVATOR AND A STABLE AQUEOUS SOLUTION OR POWDER CONTAINING THE SAME

摘要

A method for stabilizing a tissue plasminogen activator which involves adding to an aqueous solution or powder containing a tissue plasminogen activator an effective amount of a purified gelatin is disclosed. A stable aqueous solution or powder which contains a tissue plasminogen activator and an effective amount of a purified gelatin is also disclosed. The method and composition eliminate the problem of adsorption of tissue plasminogen activatOr to various laboratory equipment, and also prevent the conversion of the single-chain tissue plasminogen activatgor into a double-chain tissue plasminogen activator.