发明名称 Process for producing intermediate furanones from diol derivative and thionyl chloride
摘要 A novel process for the manufacture of the furanone of the formula <IMAGE> I is described. In this process, a diol is firstly reacted with thionyl chloride, then the sulphite formed, optionally after oxidation to the corresponding sulphate, is treated with sodium cyanide and the resulting hydroxynitrile is hydrolyzed. The furanone of formula I can be used as a starting material for the manufacture of R-(-)-pantolactone.
申请公布号 US4596879(A) 申请公布日期 1986.06.24
申请号 US19850753493 申请日期 1985.07.10
申请人 HOFFMANN-LA ROCHE INC. 发明人 FIZET, CHRISTIAN
分类号 C07D307/33;C07C67/00;C07C253/00;C07C255/12;C07D315/00;C07D327/10;(IPC1-7):C07D327/10;C07D307/32 主分类号 C07D307/33
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