| 摘要 |
PURPOSE:To produce the titled composite polysaccharide capable of controlling the absorptive decomposition property in the living body and the adsorptivity of enzyme, and useful as an immunoadsorbent and a chromatographic carrier for the purification of enzyme, etc., by bonding an amino acid (polymer) to the amino group of the polysaccharide through a peptide bond. CONSTITUTION:For example, (A) partially deacetylated chitin is dissolved in (B) a mixture of dimethylacetamide, methylpyrrolidone and lithium chloride (at weight ratios of 10:10:1), and (C) an N-carboxyamino acid anhydride is added to and dissolved in the solution under agitation to effect the bonding of the amino acid (polymer) to the amino group of the polysaccharide through a peptide bond and obtain the objective composite polysaccharide.
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