摘要 |
<p>An osmotic device for immersion in a physiological fluid, including a semipermeable sheath defining a fully enclosed cavity and being imperforate except for a plurality of pores for permitting the flow of the physiological fluid into the cavity. At least one macromolecule is disposed within the cavity and has a size larger than the pores in the sheath so that the macromolecule is prevented from leaving the cavity when the device is immersed in the physiological fluid, such physiological fluid being caused to flow into the cavity through the pores under the influence of osmotic pressure. The cavity will always contain a molecular concentration greater than the molecular concentration of physiological fluid surrounding the sheath.</p> |