MEDICINAL COMPOSITION CONTAINING AZABICYCLOOCTANE-CARBOXYLICACID

摘要

Aza bicycloheptane carboxylic acid derivatives (I) in their racemic and optically active forms, are new (where R1 is lower alkyl; R2 is OH or lower alkoxy; R3 is OH or lower alkoxy; R4 = alkyl or phenyl alkyl of at most 8C atoms). Treatment of hypertension and cardiac insufficiency. The cpds. reduce or suppress carbocypolypeptideses and enkephalinases, and so inhibit the conversion of the decapeptide angiotensine I into the octapeptide angiotensine II. /0.