| 摘要 |
NEW MATERIAL:A compound shown by the formula I (R<1> is H, or amino- protecting group; R<2> is H, OH-protecting group, or acyl; R<3> is H, or carboxy- protecting group; bond of wavy line is anti form or syn form), its salt, or salt hydrate. EXAMPLE:(6R,7R)-7-[ 2-(2-Amino-4-thiazolyl)-2-(Z-hydroxyimino)acetamide ]-3-[(2- carboxy-5-methyl-s-triazolo[1,5-a]pyrimidin-7-yl)thiomethyl]-8-oxo-5-t hia-1- azabicyclo[4,2,0]oct-2-ene-carboxylic acid. USE:An antibacterial agent agent Gram-positive and Gram-negative bacteria. PREPARATION:A compound shown by the formula II is reacted with a compound shown by the formula III, and optionally deprotected. |
