POLYAZAHETEROCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION.

摘要

Polyazaheterocyclic derivs. of formula (I) are new. In (I), R = H; lower alkyl; cycloalkyl; furyl;theinyl; pyridyl; or phenyl opt. with 1-2 halogen, lower alkyl, trifluoromethyl, alkoxy, aralkoxy, alkylthio, aralkylthio, acyl, hydroxy, amino, nitro or cyano substit. gps.. R1 = H; cyano gp.; carmaboyl; carboxyl- alkanoyl; or alkoxycarbonyl opt. with 1-2 alkoxy, cyano, nitro, phenyl, heteroaryl or -N(R3)(R4) substit. gps. in the alkoxy portion, R3,R4: alkyl; aralkyl; or gps. forming 5-7 membered heterocyclic ring with adjacent N, R2 = lower alkyl; hydroxyalkyl; acetoxyalkyl- haloalkyl- dihaloalkyl; trifluoromethyl; alkoxyalkyl- dialkoxymethyl; lower alkyl carbamoyloxy alkyl; lower alkyl thiocarbamoyl alkyl; formyl; hydroxyimino methyl; or cyano.