Hydrophilic, pressure sensitive biomedical adhesive composition.

摘要

A hydrophilic, skin-compatible, pressure sensitive, adhesive gel/hydrogel composition comprising: 25 to 50 weight pecent polvinyl pyrrolidone (PVP) having a weight average molecular weight of at least about 100000, and preferably in the range of about 100,000 to 600,000; 2 to 5 weight percent polyvinyl alcohol (PVA) preferably having a weight average molecular weight in the range of about 150,000 to 300,000; 5 to 41 weight percent polar plasticizer or humectant; 3 to 50 weight percent water; and about 0 to about 50 weight percent of a further ionic or non-ionic species. In a preferred aspect, the composition of the invention is suitable for use in an iontophoresis device to provide a hydrophilic gel matrix from which a drug is iontophoretically delivered.