发明名称 GRADUALLY RELEASING ADHESIVE FOR ORAL MUCOSA
摘要 PURPOSE:The titled preparation that is composed of a polysaccharide film containing aqueous polyhydric alcohol and active ingredients, thus showing high shape retention, high adhesion to mucous membranes, flexibility and pro longed duration of its activity and having satisfactory strength even without a support. CONSTITUTION:The titled preparation is composed of a polysaccharide film containing an aqueous polyhydric alcohol and active ingredients. The oral adhesive has high shape retention even when it is wetted with saliva and shows good gradual-release properties and medicines are absorbed through oral mucosa to cure not only stomatoses but also a variety of diseases. The polysaccharides stated above is preferably composed of acidic ones and neutral ones and sulfated polysaccharide, preferably carrangeenan, as an acidic polysaccharide and galactomannan such as locust beam gum at a weight ratio of 20/80-99/1.
申请公布号 JPS61122211(A) 申请公布日期 1986.06.10
申请号 JP19840245610 申请日期 1984.11.20
申请人 MITSUBISHI ACETATE CO LTD;SATO SEIYAKU KK 发明人 NAGAKURA YOSHIHIKO;MORIOKA SHIGEO;OKADA TAIZO;FUJII MICHIKO;MOCHIDA NAOKI;TABUCHI TAKU
分类号 A61K9/70 主分类号 A61K9/70
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