发明名称 |
Use of some 2-[2-[4-phenyl-1-piperazinyl]ethyl]-1H-naphth-[1,2-D]imidazole derivatives and their pharmaceutically acceptable salts in the treatment of cardiovascular diseases |
摘要 |
The present invention is directed to a new pharmacological use of some known naphthoimidazole derivatives. More particularly, the compounds of the invention are 2-[2-(4-phenyl-1-piperazinyl)ethyl]-1H-naphtho[1,2-d]imidazoles of formula <IMAGE> wherein R is selected from methyl and 1-methylethyl and R1 is selected from hydrogen, chloro, methoxy and trifluoromethyl and the pharmaceutically acceptable acid addition salts thereof and possess antihypertensive activity.
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申请公布号 |
US4594348(A) |
申请公布日期 |
1986.06.10 |
申请号 |
US19850698653 |
申请日期 |
1985.02.06 |
申请人 |
GRUPPO LEPETIT S.P.A. |
发明人 |
TOJA, EMILIO;BARONE, DOMENICO;BALDOLI, EMILIANA |
分类号 |
A61K31/415;A61K31/4184;A61K31/495;A61K31/496;A61P9/12;C07D235/02;(IPC1-7):A61K31/50 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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