摘要 |
<p>TITLE "A process for the preparation of ergoline derivatives" R1=H, CH3 R2=H, halogen, CH3, CN, lower alkylthio, phenylthio R7 and R8=H; R3=H, OCH3 R7=H, R3 and R8= bond R7 and R8= bond, R3=H, OCH3 R4=C1-C4 hydrocarbon R5=H, C1-C4 hydrocarbon, < IMG > phenyl A=CHR6, CH2CHR6, CH=CR6 R6=H, lower alkyl n=O, 1,2 X=O,S,NH B=CN, COOalK, CONH2 I Rg=H or B andRg=-?=W W=O,NH and their pharmaceutically acceptable salts are antiprolactinic and antihypertensive agents. Their preparation and pharmaceutical compositions containing them are also described.</p> |
申请人 |
FARMITALIA CARLO ERBA S.P.A. |
发明人 |
BERNARDI, LUIGI;CHIODINI, LAURA;MANTEGANI, SERGIO;RUGGIERI, DANIELA;TEMPERILLI, ALDEMIO;SALVATI, PATRICIA |