Process for making a stable pharmaceutical preparation of prostaglandin E compounds, and/or 15R forms thereof.

摘要

A process for making a stable pharmaceutical preparation of prostaglandin E compounds and/or 15R forms thereof is disclosed.

Prostaglandin E compounds and 15R forms thereof are known to have useful pharmacological actions even if they are used in a vary small amounts. However, they are extremely unstable and, therefore, considerably difficult in application for routine clinical purposes.

In order to remove this difficulty, prostaglandin E compounds and 15R forms thereof are formulated into a stable preparation by filling a hard capsule with a solution or a suspension thereof.