| 摘要 |
Compounds represented by formula (I), wherein R represents hydrogen, halogen, C1-4 alkyl, trifluoromethyl, phenyl or C1-4 alkoxy, n represents 0,1 or 2, A represents formula (II), wherein X represents halogen or optionally halogen-substituted C1-4 alkyl, m represents 0,1 or 2, B represents CH, N or (III), W represents -O-, formula (IV) wherein r<3>, r<4>, r<5>, r<6>, r<7>, and r<8> each represents hydrogen, hydroxy or C1-4 alkyl, k and j each represents 1, 2, or 3, l represents 0 or 1, Q represents aryl such as substituted phenyl, substituted pyridyl, etc., E and D each represents CH, N or formula (III) (provided that E and D do not represent N or formula (III) at the same time), and r<1> and r<2> each represents hydrogen, halogen or C1-4 alkyl, and Y represents O, CH2, S or SO2, provided that symbols <SIGN> between positions 1 and 2 and between positions 3 and 4 in the Y-containing tricyclic system each represents a single or double bond have antifungal and antiprotozoan effects against candasis, trichomoniasis, mycosis, etc. |
