| 摘要 |
NEW MATERIAL:Antibiotic SS21010D shown by the formula. [Physical and chemical properties] Molecular weight and molecular formula: 748, C41H52N2O11 Mass spectrum (SIMS) (M+H)<+> m/z 749. Melting point: 145 deg.C(decomposition). Specific rotatory powder: [alpha]<20>D+390 deg.(C 0.1, MeOH). Solubility: soluble in chloroform, acetone, methanol, pyridine, or acidic water, insoluble in n-hexane. Basic, yellow ish red crystal. Color reaction: positive in Dragendorff's reagent, etc. USE:A drug. An antibacterial agent and an anti-cancer. PREPARATION:A mold such as Streptomyces sp. SS21020 strain [FERM P-7798] belonging to the genus Streptomyces, capable of producing antibiotic SS21010D, inoculated into a nutrient source-containing medium, cultivated aerobically and antibiotic SS21020D is collected from the culture mixture. |
