| 摘要 |
NEW MATERIAL:A lymphokine II (molecular weight, 20,000+ or -2,000; isoelectric point, pI=6.2+ or -0.3; mobility, Rf=0.29+ or -0.02 by Disc-PAGE; solubility, soluble in water, saline water and phosphate buffer solution, hardly soluble or insoluble in ethylether, etc.; color reactions, positive to protein by Lawry reaction, etc., positive to glucide by phenol sulfuric acid method, etc.; stability, stable at 60 deg.C for 30min at 7.2pH, stable at 4.0-11.0pH at 4 deg.C for 16hr, and stable for >=1 month in frozen state at -10 deg.C). USE:Agent for suppressing the proliferation of malignant tumor cells. PREPARATION:The novel lymphokine II is produced by treating a human- originated cell capable of producing the novel lymphokine II (e.g. leukocyte, lymphocyte, established cell, etc.) with an inducing agent. The limphokine is essentially harmless to the normal human cell. |
