发明名称 NUEVOS ESTERES DE 9 -FLUORO- O CLORO- CORTICOESTEROIDES Y PROCEDIMIENTO PARA SUS PRODUCCIONES
摘要 <p>Novel esters of 9 alpha -fluoro- and chloro-corticosteroids of the formula <IMAGE> wherein Y is chlorine or OR1, R1 and R2 represent an acyl group of 2-6 carbon atoms or a benzoyl group and where R1 and R2 can be the same or different in the same molecule, R3 is methyl or fluorine in either the alpha - or beta - orientation, X is chlorine or fluorine, and the C1 C2 bond can be saturated or not, especially those compounds of the formula <IMAGE> wherein Y and R2 have the significance given above, are prepared by reacting the respective 9 beta ,11 beta -epoxy compounds with hydrogen fluoride or chloride.</p>
申请公布号 ES545560(D0) 申请公布日期 1986.06.01
申请号 ES19600005455 申请日期 1985.07.24
申请人 HOVIONE INTER LTD. 发明人
分类号 A61K31/57;A61P29/00;C07J5/00;C07J7/00;C07J71/00;(IPC1-7):C07J5/00 主分类号 A61K31/57
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