NOVEL POLYPEPTIDE AND PREPARATION THEREOF

摘要

NEW MATERIAL:The compound of formula I (Ala is alanine; Ser is serine; Leu is leucine; Thr is threonine; Val is valine, Gly is glycine; Lys is lysine; Gln is glutamine, Glu is glutamic acid; His is histidine; Tyr is tyrosine; Pro is proline; Arg is arginine; Asp is aspartic acid; n is 3-7), its acid addition salt, and its complex. USE:An agent for lowering the Ca<2+> concentration in blood. PREPARATION:The peptide or polypeptide having the amino acid sequence of formula I is prepared, and the produced constituent unit containing the peptide residue of formula II (R is active ester residue is subjected to the cyclization reaction at an arbitrary stage in the peptide-formation reaction.