2-SUBSTITUERADE -1,3-PROPYLIDENDIFOSFONATDERIVAT OCH DERAS FRAMSTAELLNING.

摘要

2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R1 and R2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. (I) .