| 摘要 |
The (thio)morpholines of the formula I <IMAGE> in which Z is O, S, SO or SO2, R<1> and R<5> can be identical or different and are H, alkyl with 1-4 C atoms, cycloalkyl with 3-7 C atoms, hydroxyalkyl with 2-4 C atoms, alkoxyalkyl with 2-8 C atoms or benzyl, R<2> is H or alkyl with 1-6 C atoms, R<3> is CH3 or -(CH2)4-NH2, R<4> is CH3 or -CH2)2-Ar and Ar is a phenyl which is unsubstituted or substituted one or more times by alkyl with 1-4 C atoms, alkoxy with 1-4 C atoms, Cl and/or CN, and their salts lower blood pressure. |
