发明名称 DIPEPTIDE COMPOUNDS HAVING PHARMACEUTICAL ACTIVITY AND COMPOSITIONS CONTAINING THEM
摘要 PCT No. PCT/EP85/00543 Sec. 371 Date Aug. 11, 1986 Sec. 102(e) Date Aug. 11, 1986 PCT Filed Oct. 16, 1985 PCT Pub. No. WO86/02353 PCT Pub. Date Apr. 24, 1986.The compounds of formula <IMAGE> (I) wherein the group <IMAGE> represents the residue of a natural amino acid selected from the group consisting of glycine, alanine, beta-alanine, phenylalanine, isoleucine, methionine, proline, aspartic acid and arginine; R represents a hydrogen atom or a C1-C4 alkyl; and their acid-addition salts with pharmaceutically acceptable organic or inorganic acids; are useful in the preventive and curative treatment of pathologic syndromes due to the lowering of glutathione (GSH) levels.
申请公布号 ZA8507912(B) 申请公布日期 1986.05.28
申请号 ZA19850007912 申请日期 1985.10.15
申请人 ZAMBON S.P.A. 发明人 ALBERTO PILOTTO;MARIO PORTELLI;ANGELO CARENZI;DAVIDE DELLA BELLA
分类号 C07D277/06;A61K38/00;C07K5/06;C07K5/078 主分类号 C07D277/06
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