发明名称 ANTI-PROTOZOAL COMPOUNDS
摘要 <p>1,4-Naphthoquinones of formula (I), methods for their preparation, pharmaceutical and veterinary formulations thereof and the use thereof in human and animal therapy are disclosed. < IMG > (I) Particularly preferred compounds of formula (I) are 2-(4'-t-butylcyclo-hexyl)-3-hydroxy-1,4-naphthoquinone and 2-hydroxy-3-(4'-t-pentylcyclo-hexyl)-1,4-naphthoquinone. The compounds are of value as antiprotozoal agents, in particular antimalarial and anticoccidial agents.</p>
申请公布号 CA1205083(A) 申请公布日期 1986.05.27
申请号 CA19820413584 申请日期 1982.10.15
申请人 WELLCOME FOUNDATION LIMITED (THE) 发明人 HUDSON, ALAN T.;RANDALL, ANTHONY W.
分类号 A61K31/05;A61K31/12;A61K31/122;A61P17/00;A61P27/02;A61P29/00;A61P33/02;A61P43/00;C07C45/00;C07C46/00;C07C50/24;C07C50/32;C07C51/08;C07C51/353;C07C51/36;C07C51/487;C07C53/134;C07C61/08;C07C61/15;C07C61/22;C07C67/00;(IPC1-7):C07C50/32 主分类号 A61K31/05
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