DECARBOXYLASE-INHIBITING FLUORINATED ALKANE DIAMINE DERIVATIVES

摘要

DECARBOXYLASE - INHIBITING FLUORINATED ALKANE DIAMINE DERIVATIVES Novel fluorinated diamine derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general Formula I: Formula 1 wherein: Rc represents hydrogen or carboxy; R1 represents hydrogen or C1-C6 alkyl; Z represents methylene or oxygen; m and n each represent 0, 1 or 2 but m + n = 1 or 2; and p represents 1 or 2.