发明名称 DERIVATIVES OF 2-BUTYROLACTONE FOR PROTECTING THE MYOCARDIUM PRESENTING AN ANTI-ARRYTHMIC ACTIVITY AND DRUGS CONTAINING SAME
摘要 The present invention relates to the products of general formula: <IMAGE> (I) in which: R represents a straight or branched alkyl group having from 2 to 5 atoms of carbon, or the group <IMAGE> represents a morpholino or piperidino group possibly substituted by 1 or 2 methyl groups; n=2 or 3; R1 and R2 considered independently each represent hydrogen or a lower alkyl group (1 to 4 carbon atoms) or R1 and R2 taken together represent a (CH2)m group where m=4 or 5, R3 being equal to H or R1 is H and R2 and R3 considered together represent (CH2)p where p is 3 or 4 the butyrolactone cycle substitutes the pyridyl group in 2', 3' or 4' position, the salts, isomers and mixtures of isomers of said products; and to a process for preparing said products and to the myocardium-protecting drugs containing same.
申请公布号 PH19547(A) 申请公布日期 1986.05.20
申请号 PH20010000298 申请日期 1983.11.08
申请人 SANOFI 发明人 CLAUDE BERNHART;WERNER CAUTREELS;PATRICK GAUTIER
分类号 A61K31/341;A61K31/443;A61P9/06;C07D213/57;C07D405/04;C07D405/12;C07D405/14;C07D413/14 主分类号 A61K31/341
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