| 摘要 |
<p>Compounds useful in the treatment of cardiovascular diseases, such as hypertension, congestive heart failure, arrhythmia, migraine, and vasospastic disorders, and intraocular hypertensive diseases such as glaucoma are represented by the formula <CHEM> or a pharmaceutically acceptable acid addition salt thereof, wherein R1 is alkyl of two to four carbon atoms; and R2 is alkyl of three or four carbon atoms; or R1 and R2 taken together with N form <CHEM> wherein n is 0, 1 or 2 and R5 and R6 are each independently lower alkyl or hydrogen; R3 is hydrogen or hydroxy; R4 is hydrogen, lower alkyl, amino, or lower alkylamino.</p> |
