发明名称 THERAPEUTIC AGENTS
摘要 <p>Compounds of formula I <IMAGE> and pharmaceutically acceptable salts thereof; in which R1 and R2, which are the same or different, are H or an optionally substituted hydrocarbon group or R1 and R2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring; R3 is an optionally substituted aromatic hydrocarbon group; and R4 is a hydrocarbon group containing at least one substituent selected from the group consisting of hydroxy and acylated derivatives thereof, optionally substituted alkoxy groups, optionally substituted cycloalkyloxy groups, optionally substituted alkylenedioxy groups, oxo and groups of formula S(O)pR5 in which p is 0, 1 or 2 and R5 is an alkyl group, said hydrocarbon group being optionally substituted by additional substituents, are useful in the treatment of depression.</p>
申请公布号 GR860092(B) 申请公布日期 1986.05.14
申请号 GR19860100092 申请日期 1986.01.15
申请人 THE BOOTS COMPANY PLC 发明人 HOUSLEY ROSINDALE JOHN;JEFFERY EDWARD JAMES;JOHNSTON NORMAN DAVID;SARGENT JEREMY BRUCE
分类号 C07D307/52;A61K31/135;A61K31/16;A61K31/165;A61K31/215;A61K31/22;A61K31/33;A61K31/4409;A61K31/4418;A61K31/445;A61K31/535;A61K31/5375;A61P25/24;A61P25/26;C07C45/63;C07C49/567;C07C67/00;C07C213/00;C07C215/38;C07C217/48;C07C217/74;C07C219/22;C07C225/18;C07C231/00;C07C231/12;C07C235/06;C07C313/00;C07C317/28;C07C323/29;C07D211/14;C07D211/30;C07D211/70;C07D213/30;C07D295/073;C07D295/08;C07D295/084;C07D295/10;C07D295/13;C07D295/145;C07D295/185;C07D317/28;C07D319/06 主分类号 C07D307/52
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