发明名称 Galactose-C-6 nitrogen mustard compounds and their uses.
摘要 <p>Compounds of the formula &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="25" wi="57" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt; wherein X is halogen; each R independently represents H, a C&lt;Sub&gt;1&lt;/Sub&gt;-C&lt;Sub&gt;4&lt;/Sub&gt; alkyl group, a C&lt;Sub&gt;2&lt;/Sub&gt;-C&lt;Sub&gt;4&lt;/Sub&gt; alkanoyl group, a phosphate group, or a sulfate, sulfonate, or benzoate group with the proviso that no more than one sulfate, sulfonate, or benzoate group is present in said compound; and R' represents R or a carbohydrate residue derived from a carbohydrate having the formula R'OH with the proviso that R' and the R on C-2 or both R groups on C-3 and C-4 together can represent an isopropylidene group; or a pharmaceutically acceptable salt thereof, are disclosed along with methods of synthesizing and using these compounds in selectively suppressing cell division in a hydrophylic tissue.</p>
申请公布号 EP0181154(A2) 申请公布日期 1986.05.14
申请号 EP19850307874 申请日期 1985.10.30
申请人 GEORGETOWN UNIVERSITY 发明人 MCPHERSON, EUGENE;SCHEIN, PHILIP S.
分类号 C12N5/06;A61K31/70;A61K31/7008;A61K31/7024;A61K31/7028;A61P35/00;A61P35/02;C07H5/06;C07H9/02;C07H9/04;C07H13/04;C07H15/12;(IPC1-7):C07H15/04 主分类号 C12N5/06
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