摘要 |
<p>Compounds of the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="25" wi="57" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>
wherein X is halogen; each R independently represents H, a C<Sub>1</Sub>-C<Sub>4</Sub> alkyl group, a C<Sub>2</Sub>-C<Sub>4</Sub> alkanoyl group, a phosphate group, or a sulfate, sulfonate, or benzoate group with the proviso that no more than one sulfate, sulfonate, or benzoate group is present in said compound; and R' represents R or a carbohydrate residue derived from a carbohydrate having the formula R'OH with the proviso that R' and the R on C-2 or both R groups on C-3 and C-4 together can represent an isopropylidene group; or a pharmaceutically acceptable salt thereof, are disclosed along with methods of synthesizing and using these compounds in selectively suppressing cell division in a hydrophylic tissue.</p> |