发明名称 Antiallergic bis-imidazolinoamino derivatives
摘要 Compounds possessing valuable therapeutic activity particularly as lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties, of the formula: <IMAGE> wherein Z is an unsubstituted normal alkylene chain of up to 8 carbon atoms or a substituted normal alkylene chain in which the substituent is lower alkyl, phenyl or benzyl containing up to 8 carbon atoms in the normal chain and up to a total of about 12 carbon atoms; X=O to S; n=0 or 1; and each R is H, lower alkyl or lower alkanoyl; and salts thereof, especially pharmaceutically-acceptable salts.
申请公布号 US4588737(A) 申请公布日期 1986.05.13
申请号 US19840684214 申请日期 1984.12.20
申请人 USV PHARMACEUTICAL CORP. 发明人 HUANG, FU-CHIH
分类号 A61K31/415;A61K31/505;A61P11/00;A61P37/08;C07C67/00;C07C213/00;C07C217/76;C07C239/00;C07C253/00;C07C255/13;C07C255/46;C07C255/54;C07C279/04;C07C279/18;C07C279/28;C07C313/00;C07C323/12;C07C323/29;C07D233/50;C07D239/14;C07D307/10;C07D307/14;C07D405/12;C07D405/14;C12N9/99;(IPC1-7):A61K31/415 主分类号 A61K31/415
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