IMIDAZOL-DERIVAT OCH SYRAADDITIONSSALTER DERAV, FORFARANDE FOR DERAS FRAMSTELLNING SAMT FARMACEUTISK KOMPOSITION INNEHALLANDE IMIDIZOL-DERIVATEN

摘要

Novel compounds I and their acid addition salts in which R is phenyl or phenylthio show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'- dichlorophenyl)-2-(N-imidazolyl- methyl)-ethanol with 4-chloromethyl- biphenyl, 4-bromomethyl-biphenyl, 1- phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide.