| 摘要 |
Compounds of the formula (I) : …<IMAGE>… and pharmaceutically acceptable salts are described, wherein: …<??>R is hydrogen or C1-2alkyl; R<3> is hydrogen; or R and R<3> together form a bond; n is one or two; R<1> is hydrogen, C1-6alkyl, C1-6alkoxy, hydroxy, halo, cyano, amino, -CONR<4>R<5>, -NHCONR<6>R<7>, -NHC(NCN)NHR<8>, -NHC(NCN)R<9>, or C1-6alkoxycarbonylamino wherein R<4> - R9 are independently hydrogen or C1-6 alkyl; and R<2> is hydrogen or C1-6alkyl; …<??>with the proviso that when n is one and R, R<2> and R<3> are hydrogen R<1> is not hydrogen, cyano or bromo or when R and R<3> together form a bond and n is one R<1> and R<2> are not both hydrogen. …<??>Processes and intermediates for their preparation are described. Pharmaceutical compositions containing them are described, as is their use as inotropic agents. |
