| 摘要 |
PURPOSE:A stimulating material for immunocyte having function to activate immunocyte in blood cell and to induce an antitumor immunocyte, obtained by bonding a nucleic acid base or its derivative to an insoluble carrier by covalent bond. CONSTITUTION:A stimulating material for antitumor imunocyte having one or more nucleic acid base, nucleoside, nucleotide, and their chemically modified derivatives on the surface, obtained by bonding the nucleic acid base, nucleoside, nucleotide, and their chemically modified derivatives having no cell activating ability in a liberated state in a suspended cell solution to an insoluble carrier, having function to induce strongly tumor damaging cell when the stimulating material is used for activating human or mouse leukocyte, the activated leukocyte is mixed with a tumor cell, the tumor cell is damaged and destroyed. EFFECT:Activating peripheral leukocyte efficiently, and capable of inducing strongly tumor damaging cell safely in good operating properties. |
