Sulfonic resins having a therapeutical activity, preparation thereof and pharmaceutical compositions containing them

摘要

A pharmaceutical compound characterized by a delayed release of the therapeutically active component, comprising a sulfonic type ion exchange resin and cis(+/-)-3-acetyloxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-metho xyphenyl)-1,5-benzothiazepin-4(5H)one, or cis(+/-)-3-hydroxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxy phenyl)-1,5-benzothiazepin-4(5H)one as a therapeutically active compound. A process for the preparation of the active compound. A pharmaceutical composition including said active compound, and use of said composition for the prophylaxis and therapy of acute and chronical coronary insufficiency and of arterial hypertension.