发明名称 |
Halogenophenyl glyceride esters for use in the prophylaxis and/or therapy of acne vulgaris |
摘要 |
The invention concerns novel glyceride esters of anti-bacterial halogenated phenols having the formula I in which Ra and Rb are independently (3-20C)alkyl or (3-20C)alkenyl; Rc and Rd are independently chloro or bromo; Re is hydrogen, chloro or bromo; and A is (1-6C)alkylene optionally bearing one or two (1-4C)alkyl substituents. The esters are of use in the prophylaxis and/or therapy of acne vulgaris. Pharmaceutical compositions for topical administration and processes for the manufacture of the esters are also provided.
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申请公布号 |
US4587262(A) |
申请公布日期 |
1986.05.06 |
申请号 |
US19830501758 |
申请日期 |
1983.06.06 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES PLC |
发明人 |
ARNOULD, JEAN C.;EVANS, JOHN R.;JONES, GERAINT;THOMSON, DAVID S. |
分类号 |
C07C69/34;A61K31/225;A61P17/00;C07C59/68;C07C69/353;(IPC1-7):A61K31/235;C07C69/00 |
主分类号 |
C07C69/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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