发明名称 |
PROCESS FOR THE PREPARATION OF 7-AMINO-3-PROPENYLCEPHALOSPORANIC ACID AND ESTERS THEREOF |
摘要 |
<p>This invention provides novel cephalosporin intermediates, 7 beta -amino-3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid and esters thereof having the general formula <IMAGE> wherein the configuration of the 3-propenyl group is Z sometimes referred to as cis- and R is hydrogen or a conventional carboxy-protecting group, and acid addition salts thereof and the metal salts of the foregoing substance wherein R is hydrogen. These compounds are useful as intermediates for preparation of orally active cephalosporins. <IMAGE></p> |
申请公布号 |
PT82436(A) |
申请公布日期 |
1986.05.01 |
申请号 |
PT19860082436 |
申请日期 |
1986.04.21 |
申请人 |
BRISTOL MYERS COMPANY |
发明人 |
HIDEAKI HOSHI;TAKAYUKI NAITO;JUN OKUMURA;YOSHIO ABE;SHIMPEI ABURAKI |
分类号 |
A61K;A61K31/545;C07C;C07D;C07D501/00;C07D501/02;C07D501/04;C07D501/16;C07D501/18;C07D501/22;C07D513/04;C07F7/10;(IPC1-7):C07D501/00 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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