| 摘要 |
<p>There is disclosed a compound of the formula (I):
<CHEM>
wherein:
@@@@ is optionally a double or single bond;
n = 0-4;
X, X min , Y, Y min are each independently H, OH, halogen, amino, nitro, lower alkyl, trifluoromethyl or lower alkoxy;
R1 is H, alkyl, OH or lower alkoxy;
R2 is H or halogen;
R2 min , R3 min , and R5 min are each independently hydrogen, alkanoyl, benzoyl, benzoyl substituted by lower alkyl, lower alkoxy, halogen, or trifluoromethyl, or
R2 min and R3 min together may be 2 min , 3 min -isopropylidene, or a pharmaceutically acceptable acid addition salt thereof.
<??>Also disclosed is a process for producing the compounds, pharmaceuticals comprising the compounds and pharmaceutical uses of the compounds. The compounds have highly desirable blood pressure lowering properties. </p> |
