发明名称 HISTARGIN-RELATED COMPOUNDS,A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 The present invention relates to compounds of the formula <CHEM> wherein A is a residual group obtained by removing one hydrogen atom from the alpha-amino group in an alpha-amino acid (excluding arginine) or a lower alkyl ester thereof; R is a hydrogen atom or a lower alkyl group, or a salt thereof, and to a process for the preparation of these compounds. The compounds are capable of inhibiting the action of angiotensin converting enzyme and can therefore be used as anti-hypertensive agents.
申请公布号 ZA8506775(B) 申请公布日期 1986.04.30
申请号 ZA19850006775 申请日期 1985.09.04
申请人 MICROBIAL CHEMISTRY RESEARCH FOUNDATION 发明人 HAMAO UMEZAWA;TOMIO TAKEUCHI;TAKAAKI AOYAGI;KEIJI OGAWA;HIRONOBU IINUMA;MAKOTO MORIGUCHI;TERUYA NOMURA;YOSHIHISA UMEDA;HIROYUKI KURODA;AKIRA OHBAYASHI
分类号 A61K31/415;A61P9/12;A61P43/00;C07D233/54;C07D233/64 主分类号 A61K31/415
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