发明名称 |
HISTARGIN-RELATED COMPOUNDS,A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
摘要 |
The present invention relates to compounds of the formula <CHEM> wherein A is a residual group obtained by removing one hydrogen atom from the alpha-amino group in an alpha-amino acid (excluding arginine) or a lower alkyl ester thereof; R is a hydrogen atom or a lower alkyl group, or a salt thereof, and to a process for the preparation of these compounds. The compounds are capable of inhibiting the action of angiotensin converting enzyme and can therefore be used as anti-hypertensive agents. |
申请公布号 |
ZA8506775(B) |
申请公布日期 |
1986.04.30 |
申请号 |
ZA19850006775 |
申请日期 |
1985.09.04 |
申请人 |
MICROBIAL CHEMISTRY RESEARCH FOUNDATION |
发明人 |
HAMAO UMEZAWA;TOMIO TAKEUCHI;TAKAAKI AOYAGI;KEIJI OGAWA;HIRONOBU IINUMA;MAKOTO MORIGUCHI;TERUYA NOMURA;YOSHIHISA UMEDA;HIROYUKI KURODA;AKIRA OHBAYASHI |
分类号 |
A61K31/415;A61P9/12;A61P43/00;C07D233/54;C07D233/64 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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