发明名称 USE OF O-SUBSTITUTED PYRUVIC ACID OXIMES FOR THE PROPHYLAXIS AND/OR TREATMENT OF HEART AND CIRCULATORY DISEASES,AS WELL AS CORRESPONDING MEDICAMENTS
摘要 Medicinal use of propionic acid derivatives of the general formula I <IMAGE> in which R1 and R2 are identical or different and are hydrogen, halogen, trifluoromethyl, alkyl, hydroxyl, acyloxy, alkoxy radicals or together are the methylenedioxy group and X is a straight-chain, saturated or unsaturated alkylene group which has 2-4 C atoms and is optionally substituted in the beta or gamma position to the nitrogen by an alkyl group, and the physiologically acceptable salts, esters and amides thereof for the prophylaxis and/or treatment of cardiovascular disorders, especially ischaemic cardiac disorders such as heart failure, angina pectoris or myocardial infarct.
申请公布号 ZA8505340(B) 申请公布日期 1986.04.30
申请号 ZA19850005340 申请日期 1985.07.16
申请人 BOEHRINGER MANNHEIM GMBH. 发明人 HANS KUEHNLE;HANS PETER WOLFF
分类号 A61K31/19;A61K31/15;A61K31/215;A61K31/22;A61K31/275;C07D317/58 主分类号 A61K31/19
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