摘要 |
<p>Described are peptides that have, as partial sequence of a larger peptide, or exclusively, the amino acid sequence of the formula I <IMAGE> (I) ArgSerGlyGlyMetValLysSerAsnPheValProThrAsnValGlySer- +TR LysAlaPhe- in which the cysteine residues can form intra- or inter-molecular disulphide bridges, and derivatives thereof having an amidated terminal carboxy group and/or an acylated terminal amino group, and their salts, DNA sequences that code for the mentioned peptides, micro-organisms that contain these DNA sequences, processes for the manufacture thereof, pharmaceutical preparations that contain the mentioned peptides in the form of their amides, and the use of these peptide-amides for the treatment of coronary circulation disorders and bone metabolism disorders.</p> |