发明名称 OLIGOPEPTIDES THEIR INTERMEDIATES METHOD FOR THEIR PREPARATION
摘要 <p>Described are peptides that have, as partial sequence of a larger peptide, or exclusively, the amino acid sequence of the formula I <IMAGE> (I) ArgSerGlyGlyMetValLysSerAsnPheValProThrAsnValGlySer- +TR LysAlaPhe- in which the cysteine residues can form intra- or inter-molecular disulphide bridges, and derivatives thereof having an amidated terminal carboxy group and/or an acylated terminal amino group, and their salts, DNA sequences that code for the mentioned peptides, micro-organisms that contain these DNA sequences, processes for the manufacture thereof, pharmaceutical preparations that contain the mentioned peptides in the form of their amides, and the use of these peptide-amides for the treatment of coronary circulation disorders and bone metabolism disorders.</p>
申请公布号 GR860081(B) 申请公布日期 1986.04.29
申请号 GR19860100081 申请日期 1986.01.14
申请人 CIBA - GEIGY AG 发明人 DR. HENDRIK SIMONS JANSZ;DR. CORNELIS JOSEPHUS MARIA LIPS;SR. STEENBERGH HERMAN PAUL;RINK HANS;SIEBER PETER
分类号 G01N33/50;A61K35/74;A61K38/00;A61K38/22;A61K38/23;A61K39/395;A61P1/00;A61P3/00;A61P9/04;A61P9/08;A61P9/12;A61P25/00;C07K1/113;C07K7/00;C07K14/00;C07K14/575;C07K14/585;C12N1/00;C12N15/00;C12N15/09;C12N15/16;C12P21/00;C12P21/02;C12R1/19 主分类号 G01N33/50
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